Food
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Beer | Temporarily lowers your Perception by 1 | In a fridge by the Junktown Entrance | |
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Booze | Temporarily lowers your Perception by 1 | In a fridge by the Junktown Entrance; sold by Vance in the Hub Old Town | |
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Iguana-on-a-Stick | None | Sold by Iguana Bob in the Hub Downtown | |
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Iguana-on-a-Stick | None | Sold by Iguana Bob in the Hub Downtown | |
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Fruit | Restores a few hit points | In a fridge by the Junktown Entrance | |
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Nuka-Cola | Drink too many of these and you may become addicted | In a fridge by the Junktown Entrance; sold in the General Store in the Hub and by Tine in the Boneyard |
Chemicals
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Antidote | Cures poison | Bring Scorpian tail to Razlo in Shady Sands; sold by Vance in the Hub Old Town | |
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Buffout | Temporarily increases strength and reflexes; highly addictive | Sold by Vance in the Hub Old Town | |
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Mentats | Temporarily increases mental abilities; highly addictive | Sold in the General Store in the Hub and by Vance in Old Town in the Hub | |
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Psycho | Temporarily increases combat abilities; highly addictive | Sold in the General Store in the Hub and by Vance in Old Town in the Hub | |
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RadAway | Cures Radiation damage | Sold in the General Store in the Hub and by Vance in Old Town in the Hub | |
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Rad-X | Provides protection from radiation and by Vance in Old Town in the Hub | In a locker on the Living Quarters in the Vault under Necropolis; in several places in the Glow | |
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Stimpack | Immediately heals 10-20 HPs | Many locations throughout the game | |
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Super Stimpack | Heals more HPs than a regular Stimpack, but after a few minutes you will lose some of those HPs | Sold in the General Store in the Hub and by Vance in Old Town in the Hub |
Miscellaneous
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Back Pack | Store items inside | On some shelves in the Backroom of Killian's store in Junktown; in a desk in the Hall of Necropolis; on a bookshelf in Jon Zimmerman's basement in the Boneyard | |
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Bag | Store items inside | On a bookshelf in the Casino in Junktown; on a bookshelf in Jon Zimmerman's basement in the Boneyard | |
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Bottle Caps | Used for trade | Many locations throughout the world | |
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Doctor's Bag | Improves use of Doctor skill | On a bookshelf in Jon Zimmerman's basement in the Boneyard; in a Fridge in the Library in the Boneyard | |
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Dynamite | Causes a powerful explosion; set the timer, drop it, and then run | Vault 15, In the fridge in the Raider Camp; In a desk in the Hotel area of Necropolis; sold by Killian in Junktown and by Tine in the Boneyard | |
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Electronic Lock Pick | Unlocked locked doors | Jasmine in the Thieves' Circle in the Hub after you steal the Necklace for Loxley | |
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First Aid Kit | Improves use of First Aid skill | Sold by Vance in Old Town in the Hub | |
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Flare | Creates light for a short period of time | Vault 15; sold by Killian in Junktown and by Tine in the Boneyard | |
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Geiger Counter | Detects your current radiation level | Sold in the General Store in the Hub and in Jake's Weapons in the Hub; in lockers on the fourth and fifth level of the Glow | |
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Lockpicks | Improves your lock picking skill | In the Fridge in the Raider Camp; on a bookshelf near the Hall of Necropolis; in a desk in the Hall of Necropolis | |
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Motion Sensor | Detect all creatures in the area | Sold in the General Store in the Hub; in lockers on the first and fifth levels of the Glow | |
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Plastic Explosives | Causes a powerful explosion; set the timer, drop it, and then run | On a body on the second level of the Glow; sold by Tine in the Boneyard | |
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Radio | Listen in on enemy communications | Lars in Junktown, Sold in the General Store in the Hub | |
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Rope | Can be used to climb up or down things you couldn't otherwise climb through | Seth in Shady Sands; On some shelves in the Backroom of Killian's store in Junktown; sold in the General Store in the Hub | |
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Scorpian Tail | Bring to Razlo in Shady Sands for an Antidote | Radscorpians | |
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Stealth Boy | Renders you nearly invisible while in use | In a locker on the fifth level of the Glow; In a locker on the third lair level of the Cathedral | |
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Tool | Improves your Repair ability | Doc Morbid in Junktown, Sold in the General Store in the Hub; in a desk in the Hall of Necropolis |
Books
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Big Book of Science | Improves your Science skill; the higher your skill, the less you will gain | Sold in the General Store in the Hub, and in the Library in the Hub | |
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Deans Electronics | Improves your Repair skill; the higher your skill, the less you will gain | Sold in the General Store in the Hub, and in the Library in the Hub; given to you by the Ghoul leader in the sewers beneath Necropolis when you return with the Junk | |
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First Aid Book | Improves your First Aid Skill; the higher your skill, the less you will gain | Vault 15; sold in the General Store in the Hub, and in the Library in the Hub | |
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Guns and Bullets | Improves your Small Guns skill; the higher your skill, the less you will gain | Sold in the Library in the Hub; in a desk in the Hall of Necropolis | |
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Scout Handbook | Improves your Outdoorsman skill; the higher your skill, the less you will gain | Sold in the General Store in the Hub, and in the Library in the Hub |
Quest
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Blue Pass Key | Open the elevator in the northwest corner of the last three levels of the Glow | On a body in the southwest corner of the fourth level of the Glow | |
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Bug | Plant on Gizmo in his office in the Casino to prove his guilt in the attempt on Killian's life | From Killian in Junktown after you agree to help him prove that Gizmo tried to kill him | |
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C.O.C Badge | Open the locked door in the sanctuary on the first level of the Cathedral | Barter with or steal from one of the people on the first level of the Cathedral | |
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C.O.C Badge | Open the locked door on the first level of the Cathedral leading to the back room | Kill Morpheus on the top level of the Cathedral or steal it from him | |
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Dog Tags | Bring to Gizmo in the Casino in Junktown to prove that you have killed Killian | Killian in his shop in Junktown | |
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Junk | Fix the Water Pump in the Watershed in Necropolis | In the sewers beneath the Watershed in Necropolis | |
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Junk | Bring back to Miles in Adytun in the Boneyard to repair thier hydroponic farms | On a body in the Warehouse area of the Boneyard | |
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Necklace | Bring to Loxley in the Thieves' Circle in Old Town to join the Thieves' Guild | Daren Hightower's strongbox in the Heights in the Hub | |
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Psychic Nullifier | Pass through the passage leading to the Master without taking damage | Gideon on the second level of the Vault under the Cathedral | |
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Red Pass Key | Open the elevator in the northwest corner of the levels 3, 4, and 6 of the Glow | On a body in the northeast corner of the second level of the Glow | |
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Security Card | Gain access to the Vats Control Computer in the Vats Control Room in the Military Base | One of the Cathedral technicians in the Vats Control Room in the Military Base | |
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Small Piece of Machinery | Give to Kyle on the third level of the Brotherhood for Powered Armor | In the locker in Rombus' room on the first level of the Brotherhood | |
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Tape Recorder | Carry while getting Gizmo to confess his attempt on Killian's life to prove his guilt | From Killian in Junktown after you agree to help him prove that Gizmo tried to kill him | |
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Urn | Steal from the bar in the Skum Pitt in Junktown | Bring the Urn to Vinnie at the back of the Crash House to earn the trust of the Skulz | |
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Water Chip | Bring to Vault 13 to end their water crisis | On the third level of Vault 12 under Necropolis | |
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Yellow Pass Key | Open the elevator in the southwest corner of the first three levels of the Glow | On a body at the north end of the first level of the Glow |